+\textcolor{blue}{\textbf{\textsc{Answer :} Your remark is very interesting. We have observed that the optimal solution of the integer program is often obtained after the exploration of very few nodes of the Branch-and-Bound-tree. Therefore we conducted new simulations by applying your idea. That is to say we have stopped the resolution of the Branch-and-Bound method after a time threshold empirically defined and we retain the best feasible
+solution found by the solver. This approach allows to improve significantly the results with multirounds, especially for MuDiLCO-7.}}