From: couchot Date: Fri, 22 Mar 2013 10:53:56 +0000 (+0100) Subject: closedGenomes X-Git-Url: https://bilbo.iut-bm.univ-fcomte.fr/and/gitweb/ancetre.git/commitdiff_plain/014ab041d18a034bfd4827cc403871e4f28776d8?ds=sidebyside;hp=--cc closedGenomes --- 014ab041d18a034bfd4827cc403871e4f28776d8 diff --git a/closedgenomes.tex b/closedgenomes.tex index 7d84b64..bfe1c1b 100644 --- a/closedgenomes.tex +++ b/closedgenomes.tex @@ -2,7 +2,7 @@ The approach is further based on the ability to decide how far is each genome from each others. To achieve this, we combine XXX metrics which are detailed in this part. -\subsection{Core SNP based metric} +\subsection{Core SNP based Metric} Due to the definition of the core genome, for each element $\dot{x}$ in this set, there is a gene $x \in \dot{x}$ in each genome. Let us consider a class @@ -33,7 +33,7 @@ without considering the number of SNP it contains. % plus il y a de diff, plus le nombre est élevé -\subsection{Symmetric Difference based metric} +\subsection{Symmetric Difference based Metric} The third metric consider the symmetric difference $\Delta$ between the two sets $G_1$ and $G_2$ of genes recalled hereafter $$ @@ -50,9 +50,23 @@ one. This metric is equal to the Hamming distance between the two corresponding vectors of Boolean values. +% plus il y a de diff, plus le nombre est élevé + + \subsection{} % 4/ Using EPFL method -% 5/ On size of the biggest syntheny bloc -% 6/ On average size of syntheny blocs -% 7/ On number of syntheny blocs. +\subsection{Shared Synteny based Metric} +Given two genomes abstracted as sequences of classes, it is classical +to computes all the maximum shared synteny chains. + +% Attention ici, moins il y a de diff, plus le nombre est élevé +There are then three issues with such a set of shared synteny chains: +\begin{itemize} +\item let $m_{Y}$ be the metric, which returns the +length of the largest chains; +\item let $m_{\overline{Y}}$ be the metric, which returns the +average length of synteny chains; +\item finally, let $m_{|Y|}$ be the metric, which returns the +number of synteny chains. +\end{itemize}